TVNUM Seminar Room (a124) Place du Levant 2, Stévin Building, 1st floor -- Monday, 01 September 2014 at 11:00 (45 min.)
{
"name":"How using DCE-MRI and registration to measure the concentration of the contrast agent ([CA]) inside the human and guinea-pigs (GP) cochlea?",
"description":"How using DCE-MRI and registration to measure the concentration of the contrast agent (CA) inside the human and guinea-pigs (GP) cochlea? Due to the tightness of the blood-labyrinth barrier (BLB) few medium contrast reaches the inner ear resulting to a low received signal. Furthermore, the sizes of the different compartments inside the ear require a good spatial resolution. We are currently trying to design some T1-weigthed MRI sequences and a protocol to quantify the amount of CA along the time. We have performed two classes of experiments. Firstly by using a 4.7T scanner and GP and secondly using a Siemens 3T scanner and human controls. Primarily results highlight a BLB's porosity change in GP with ear infections. Also, we are currently using registration to precisely and automatically quantify the concentration of CA in the different compartments.",
"startDate":"2014-09-01",
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"startTime":"11:00",
"endTime":"11:45",
"location":"TVNUM Seminar Room (a124) Place du Levant 2, Stévin Building, 1st floor",
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How using DCE-MRI and registration to measure the concentration of the contrast agent (CA) inside the human and guinea-pigs (GP) cochlea? Due to the tightness of the blood-labyrinth barrier (BLB) few medium contrast reaches the inner ear resulting to a low received signal. Furthermore, the sizes of the different compartments inside the ear require a good spatial resolution. We are currently trying to design some T1-weigthed MRI sequences and a protocol to quantify the amount of CA along the time. We have performed two classes of experiments. Firstly by using a 4.7T scanner and GP and secondly using a Siemens 3T scanner and human controls. Primarily results highlight a BLB's porosity change in GP with ear infections. Also, we are currently using registration to precisely and automatically quantify the concentration of CA in the different compartments.
